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| Pretzer, Carina; Druzhinina, Irina S.; Amaro, Carmen; Benediktsdottir, Eva; Hedenstroem, Ingela; Hervio-heath, Dominique; Huhulescu, Steliana; Schets, Franciska M.; Farnleitner, Andreas H.; Kirschner, Alexander K. T.. |
| Coastal marine Vibrio cholerae populations usually exhibit high genetic diversity. To assess the genetic diversity of abundant V. cholerae non-O1/non-O139 populations in the Central European lake Neusiedler See, we performed a phylogenetic analysis based on recA, toxR, gyrB and pyrH loci sequenced for 472 strains. The strains were isolated from three ecologically different habitats in a lake that is a hot-spot of migrating birds and an important bathing water. We also analyzed 76 environmental and human V. cholerae non-O1/non-O139 isolates from Austria and other European countries and added sequences of seven genome-sequenced strains. Phylogenetic analysis showed that the lake supports a unique endemic diversity of V. cholerae that is particularly rich in... |
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| Ano: 2017 |
URL: http://archimer.ifremer.fr/doc/00366/47756/47802.pdf |
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| Le Roux, Frederique; Wegner, K. Mathias; Baker-austin, Craig; Vezzulli, Luigi; Osorio, Carlos R.; Amaro, Carmen; Ritchie, Jennifer M.; Defoirdt, Tom; Destoumieux-garzon, Delphine; Blokesch, Melanie; Mazel, Didier; Jacq, Annick; Cava, Felipe; Gram, Lone; Wendling, Carolin C.; Strauch, Eckhard; Kirschner, Alexander; Huehn, Stephan. |
| Global change has caused a worldwide increase in reports of Vibrio-associated diseases with ecosystem-wide impacts on humans and marine animals. In Europe, higher prevalence of human infections followed regional climatic trends with outbreaks occurring during episodes of unusually warm weather. Similar patterns were also observed in Vibrio-associated diseases affecting marine organisms such as fish, bivalves and corals. Basic knowledge is still lacking on the ecology and evolutionary biology of these bacteria as well as on their virulence mechanisms. Current limitations in experimental systems to study infection and the lack of diagnostic tools still prevent a better understanding of Vibrio emergence. A major challenge is to foster cooperation between... |
| Tipo: Text |
Palavras-chave: Global warming; Human health; Aquaculture; Interactions; Animal model; Bacterial disease; Genome plasticity; European network. |
| Ano: 2015 |
URL: http://archimer.ifremer.fr/doc/00278/38952/37494.pdf |
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